Michael Eisen, a geneticist at University of California,
Berkeley, has written a blog post concerning the CRISPR dispute, the Bayh-Dole
Act and academic science. Notably, Dr.
Eisen is running for the U.S. Senate in California. Dr. Eisen is essentially critical of the
Bayh-Dole Act for skewing incentives toward commercially valuable research,
complicating accessing research, slowing the progress of research and creating
incentives for researchers to “behave badly.”
Here is an excerpt from his post:
Academic science is, after all, largely funded by the public.
By all rights discoveries made on with public funds should belong to
the public. And not too long ago they did. But legislation passed in 1980 – the
Bayh-Dole Act – gave universities the right to claim patents on inventions made
by their researchers on the public dime. Prior to 1980 these patents
belonged to the federal government and many languished unused. The logic of
Bayh-Dole was that, if they owned patents in their work, universities and other
grantees would be incentivized to have their inventions turned into products,
thereby benefiting the public.
But this is not how things worked out. Encouraged by a small
number of patents that made huge sums, universities developed massive
infrastructure to profit from their researchers. Not only do they spend
millions on patents, they’ve turned every interaction scientists have with each
other into an intellectual property transaction. Everything I get from or send
to a colleague at another academic institution involves a complex legal
agreement whose purpose is not to promote science but to protect the
university’s ability to profit from hypothetical inventions that might arise
from scientists doing what we’re supposed to do – share our work with each other.
And the idea that this system promotes the
transformation of inventions made with public funding into products is
laughable. CRISPR is a perfect case in point. The patent battle between UC and
The Broad is likely to last for years. Meanwhile companies interested in
actually developing CRISPR into new products are stymied by a combination of a
lack of clarity about with whom to negotiate, and universities being
difficult negotiating partners.
It would be so much easier if the US government simply placed
all work arising from federal dollars into the public domain. We have a robust
science and technology industry ready to exploit new ideas, and entrepreneurs
and venture capitalists eager to fill in where existing companies are
uninterested. Taxpayers would benefit by allowing the market, and not
university licensing offices, to decide whose ideas and products make the best
use of publicly funded inventions.
And most importantly we all would benefit returning academic
science to its roots in basic discovery oriented research. We see with CRISPR
the toxic effects of turning academic institutions into money hungry
hawkers of intellectual property. Pursuit of patent riches has
transformed The Broad Institute, which houses some of the most talented
scientists working today, into a prominent purveyor of calumny.
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